Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

RATIONALE: Disruption in subcellular targeting of Ca(2+) signaling complexes secondary to changes in cardiac myocyte structure may contribute to the pathophysiology of a variety of cardiac diseases, including heart failure (HF) and certain arrhythmias. OBJECTIVE: To explore microdomain-targeted remo...

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Bibliografische gegevens
Gepubliceerd in:Circ Res
Hoofdauteurs: Sanchez-Alonso, Jose L., Bhargava, Anamika, O’Hara, Thomas, Glukhov, Alexey V., Schobesberger, Sophie, Bhogal, Navneet, Sikkel, Markus B., Mansfield, Catherine, Korchev, Yuri E., Lyon, Alexander R., Punjabi, Prakash P., Nikolaev, Viacheslav O., Trayanova, Natalia A., Gorelik, Julia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2016
Onderwerpen:
Cellular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045818/
https://ncbi.nlm.nih.gov/pubmed/27572487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308698
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