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Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin
Resisting cell death is one of the hallmarks of cancer, and represents a common problem resulting in ineffective cancer therapy. To overcome resistance to apoptosis, we designed an antibody-based therapy strategy using Kv10.1 as a target. Kv10.1 is a voltage-gated potassium channel, which has been i...
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| Publicado no: | Eur Biophys J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045482/ https://ncbi.nlm.nih.gov/pubmed/27350552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-016-1149-7 |
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