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TREM-2 serves as a negative immune regulator through Syk pathway in an IL-10 dependent manner in lung cancer
During infection, triggering receptor expressed on myeloid cells-2 (TREM-2) restrains dendritic cells (DCs) and macrophages (MΦs) phagocytosis, as well as reduces pro-inflammatory cytokines release through DNAX-activation protein 12 (DAP12) signaling. However, the role of TREM-2 signaling in cancer...
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| Wydane w: | Oncotarget |
|---|---|
| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Impact Journals LLC
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045421/ https://ncbi.nlm.nih.gov/pubmed/27102437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8813 |
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