Comparative proteomics of exosomes secreted by tumoral Jurkat T cells and normal human T cell blasts unravels a potential tumorigenic role for valosin-containing protein

We have previously characterized that FasL and Apo2L/TRAIL are stored in their bioactive form inside human T cell blasts in intraluminal vesicles present in multivesicular bodies. These vesicles are rapidly released to the supernatant in the form of exosomes upon re-activation of T cells. In this st...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Bosque, Alberto, Dietz, Lisa, Gallego-Lleyda, Ana, Sanclemente, Manuel, Iturralde, María, Naval, Javier, Alava, María Angeles, Martínez-Lostao, Luis, Thierse, Hermann-Josef, Anel, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045396/
https://ncbi.nlm.nih.gov/pubmed/27086912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8678
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