Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer

Historically, understanding of acquired resistance (AQR) to combination treatment has been based on knowledge of resistance to its component agents. To test whether an altered drug interaction could be an additional factor in AQR to combination treatment, models of AQR to combination and single agen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bhattacharya, Bhaskar, Low, Sarah Hong Hui, Chong, Mei Ling, Chia, Dilys, Koh, King Xin, Sapari, Nur Sabrina, Kaye, Stanley, Hung, Huynh, Benoukraf, Touati, Soong, Richie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045388/
https://ncbi.nlm.nih.gov/pubmed/27081080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8692
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