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Circulating cell-free DNA has a high degree of specificity to detect exon 19 deletions and the single-point substitution mutation L858R in non-small cell lung cancer

Detection of an epidermal growth factor receptor (EGFR) mutation in circulating cell-free DNA (cfDNA) is a noninvasive method to collect genetic information to guide treatment of lung cancer with tyrosine-kinase inhibitors (TKIs). However, the association between cfDNA and detection of EGFR mutation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Qian, Xin, Liu, Jia, Sun, Yuhui, Wang, Meifang, Lei, Huaiding, Luo, Guoshi, Liu, Xianjun, Xiong, Chang, Liu, Dan, Liu, Jie, Tang, Yijun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045385/
https://ncbi.nlm.nih.gov/pubmed/27081078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8684
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