The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells

HSP60 undergoes changes in quantity and distribution in some types of tumors suggesting a participation of the chaperonin in the mechanism of transformation and cancer progression. Suberoylanilide hydroxamic acid (SAHA), a member of a family of histone deacetylase inhibitors (HDACi), has anti-cancer...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Campanella, Claudia, D'Anneo, Antonella, Gammazza, Antonella Marino, Bavisotto, Celeste Caruso, Barone, Rosario, Emanuele, Sonia, Lo Cascio, Filippa, Mocciaro, Emanuele, Fais, Stefano, De Macario, Everly Conway, Macario, Alberto J.L., Cappello, Francesco, Lauricella, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045361/
https://ncbi.nlm.nih.gov/pubmed/26700624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6680
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