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Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis

Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using Xenopus we show that Cp110 inhibits cilia formation at high le...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Walentek, Peter, Quigley, Ian K, Sun, Dingyuan I, Sajjan, Umeet K, Kintner, Christopher, Harland, Richard M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045295/
https://ncbi.nlm.nih.gov/pubmed/27623009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17557
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