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ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics

Centrosomes are critical sites for orchestrating microtubule dynamics, and exhibit dynamic changes in size during the cell cycle. As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure proper chromosome segregation. We report a new role...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Stubenvoll, Michael D., Medley, Jeffrey C., Irwin, Miranda, Song, Mi Hye
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045193/
https://ncbi.nlm.nih.gov/pubmed/27689799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006370
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