A randomized controlled trial of subantimicrobial-dose doxycycline to prevent unscheduled bleeding with continuous oral contraceptive pill use()

BACKGROUND: Unscheduled bleeding is the main side effect of continuous oral contraceptive pills (OCPs) and has been correlated with the up-regulation of matrix metalloprotineases (MMPs). The study objective was to determine if prophylactic administration of doxycycline (an MMP inhibitor at low suban...

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Veröffentlicht in:Contraception
Hauptverfasser: Kaneshiro, Bliss, Edelman, Alison, Carlson, Nichole E., Nichols, Mark, Forbes, Marci Messerle, Jensen, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045031/
https://ncbi.nlm.nih.gov/pubmed/22067758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2011.08.006
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