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Glibenclamide population pharmacokinetic/pharmacodynamic modeling in South African type 2 diabetic subjects

AIM: To determine the effective dose of glibenclamide by quantifying the dose–response relationship in South African type 2 diabetic patients. PATIENTS AND METHODS: A total of 24 type 2 diabetic patients participated in a glibenclamide dose-escalation study during which glibenclamide, glucose, and i...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol
Main Authors: Rambiritch, Virendra, Naidoo, Poobalan, Pillai, Goonaseelan
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044993/
https://ncbi.nlm.nih.gov/pubmed/27713650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S102674
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