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Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions

Fibrillin-1 is a large glycoprotein encoded by the FBN1 gene in humans. It provides strength and elasticity to connective tissues and is involved in regulating the bioavailability of the growth factor TGFβ. Mutations in FBN1 may be associated with depleted or abnormal adipose tissue, seen in some pa...

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Библиографические подробности
Опубликовано в: :Mol Genet Metab
Главные авторы: Davis, Margaret R., Arner, Erik, Duffy, Cairnan R.E., De Sousa, Paul A., Dahlman, Ingrid, Arner, Peter, Summers, Kim M.
Формат: Artigo
Язык:Inglês
Опубликовано: Academic Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044862/
https://ncbi.nlm.nih.gov/pubmed/27386756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.06.009
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