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NF-κB and IRF1 Induce Endogenous Retrovirus K Expression via Interferon-Stimulated Response Elements in Its 5′ Long Terminal Repeat

Thousands of endogenous retroviruses (ERV), viral fossils of ancient germ line infections, reside within the human genome. Evidence of ERV activity has been observed widely in both health and disease. While this is most often cited as a bystander effect of cell culture or disease states, it is uncle...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Manghera, Mamneet, Ferguson-Parry, Jennifer, Lin, Rongtuan, Douville, Renée N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044829/
https://ncbi.nlm.nih.gov/pubmed/27512062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01503-16
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