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The RNA exosome channeling and direct access conformations have distinct in vivo functions
The RNA exosome is a 3′-5′ ribonuclease complex that is composed of nine core subunits and an essential catalytic subunit, Rrp44. Two distinct conformations of Rrp44 were revealed in previous structural studies, suggesting that Rrp44 may change its conformation to exert its function. In the channeli...
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| Publicado no: | Cell Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5044803/ https://ncbi.nlm.nih.gov/pubmed/27653695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.059 |
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