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Prediction and validation of protein–protein interactors from genome-wide DNA-binding data using a knowledge-based machine-learning approach

The ability to accurately predict the DNA targets and interacting cofactors of transcriptional regulators from genome-wide data can significantly advance our understanding of gene regulatory networks. NKX2-5 is a homeodomain transcription factor that sits high in the cardiac gene regulatory network...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Waardenberg, Ashley J., Homan, Bernou, Mohamed, Stephanie, Harvey, Richard P., Bouveret, Romaric
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043580/
https://ncbi.nlm.nih.gov/pubmed/27683156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160183
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