Comparative Pre-Emptive Analgesic Efficacy Study of Novel Antiepileptic Agents Lamotrigine and Topiramate in Patients Undergoing Major Surgeries at a Tertiary Care Hospital: A Randomized Double Blind Clinical Trial

BACKGROUND: Central nervous sensitization, following surgical injury, leads to postoperative pain hypersensitivity due to lowered pain threshold in peripheral nociceptors and increased excitability of spinal neurons. Pre-emptive analgesia is intended to decrease pain perception and overall analgesic...

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Detalles Bibliográficos
Publicado en:Ann Neurosci
Autores principales: Gupta, Ankush, Bhosale, Uma A., Shah, Priyank, Yegnanarayan, Radha, Sardesai, Shalini
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043339/
https://ncbi.nlm.nih.gov/pubmed/27721585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000449182
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