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Importance of metabolic rate to the relationship between the number of genes in a functional category and body size in Peto's paradox for cancer

Elucidation of tumour suppression mechanisms is a major challenge in cancer biology. Therefore, Peto's paradox, or low cancer incidence in large animals, has attracted focus. According to the gene-abundance hypothesis, which considers the increase/decrease in cancer-related genes with body size...

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Detaylı Bibliyografya
Yayımlandı:R Soc Open Sci
Asıl Yazarlar: Takemoto, Kazuhiro, Ii, Masato, Nishizuka, Satoshi S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043308/
https://ncbi.nlm.nih.gov/pubmed/27703689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.160267
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