Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression

Interleukin-6 (IL-6), one of the most important inflammatory cytokines, plays a pivotal role in metastasis and stemness of solid tumors. However, the underlying mechanisms of IL-6 in HCC metastasis remain unclear. In the present study, we demonstrated that stemness and metastatic potential of HCC ce...

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Pubblicato in:Am J Cancer Res
Autori principali: Wang, Chao-Qun, Sun, Hao-Ting, Gao, Xiao-Mei, Ren, Ning, Sheng, Yuan-Yuan, Wang, Zheng, Zheng, Yan, Wei, Jin-Wang, Zhang, Kai-Li, Yu, Xin-Xin, Zhu, Yin, Luo, Qin, Yang, Lu-Yu, Dong, Qiong-Zhu, Qin, Lun-Xiu
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043100/
https://ncbi.nlm.nih.gov/pubmed/27725896
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