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N-Methyl D-Aspartate Receptor Antagonist Kynurenic Acid Affects Human Cortical Development

Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan degradation, acts as an endogenous N-methyl-D-aspartate receptor (NMDAR) antagonist. Elevated levels of KYNA have been observed in pregnant women after viral infections and are considered to play a role in neurodevelopmental disorders. Ho...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Bagasrawala, Inseyah, Zecevic, Nada, Radonjić, Nevena V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043058/
https://ncbi.nlm.nih.gov/pubmed/27746712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00435
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