Rapid atrial pacing induces myocardial fibrosis by down-regulating Smad7 via microRNA-21 in rabbit

Tachycardia-induced atrial fibrosis is a hallmark of the structural remodeling of atrial fibrillation (AF). The mechanisms underlying tachycardia-induced atrial fibrosis remain unclear. In our previous study, we found that Smad7-downregulation promoted the development of atrial fibrosis in AF. Fibro...

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Bibliografski detalji
Izdano u:Heart Vessels
Glavni autori: He, Xuyu, Zhang, Kunyi, Gao, Xiuren, Li, Liwen, Tan, Hong, Chen, Jiyan, Zhou, Yingling
Format: Artigo
Jezik:Inglês
Izdano: Springer Japan 2016
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043001/
https://ncbi.nlm.nih.gov/pubmed/26968995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00380-016-0808-z
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