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Gene Editing: Powerful New Tools for Nephrology Research and Therapy

Biologic research is experiencing a transformation brought about by the ability of programmable nucleases to manipulate the genome. In the recently developed CRISPR/Cas system, short RNA sequences guide the endonuclease Cas9 to any location in the genome, causing a DNA double–strand break (DSB). Rep...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Miyagi, Ayano, Lu, Aiwu, Humphreys, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042678/
https://ncbi.nlm.nih.gov/pubmed/27358322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020146
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