Polymorphisms in α-Defensin–Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux

The contribution of genetic variation to urinary tract infection (UTI) risk in children with vesicoureteral reflux is largely unknown. The innate immune system, which includes antimicrobial peptides, such as the α-defensins, encoded by DEFA1A3, is important in preventing UTIs but has not been invest...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Schwaderer, Andrew L., Wang, Huanyu, Kim, SungHwan, Kline, Jennifer M., Liang, Dong, Brophy, Pat D., McHugh, Kirk M., Tseng, George C., Saxena, Vijay, Barr-Beare, Evan, Pierce, Keith R., Shaikh, Nader, Manak, J. Robert, Cohen, Daniel M., Becknell, Brian, Spencer, John D., Baker, Peter B., Yu, Chack-Yung, Hains, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042661/
https://ncbi.nlm.nih.gov/pubmed/26940096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060700
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