Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

BACKGROUND & AIMS: Netrin-1, a multifunctional secreted protein, is up-regulated in cancer and inflammation. Netrin-1 blocks apoptosis induced by the prototypical dependence receptors deleted in colorectal carcinoma and uncoordinated phenotype-5. Although the unfolded protein response (UPR) trig...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Lahlali, Thomas, Plissonnier, Marie-Laure, Romero-López, Cristina, Michelet, Maud, Ducarouge, Benjamin, Berzal-Herranz, Alfredo, Zoulim, Fabien, Mehlen, Patrick, Parent, Romain
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042567/
https://ncbi.nlm.nih.gov/pubmed/28174720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.12.011
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