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K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts

BACKGROUND: Cancer cells have an increased demand for amino acids and require transport even of non-essential amino acids to support their increased proliferation rate. Besides their major role as protein synthesis precursors, the two proteinogenic sulfur-containing amino acids, methionine and cyste...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: De Sanctis, Gaia, Spinelli, Michela, Vanoni, Marco, Sacco, Elena
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042513/
https://ncbi.nlm.nih.gov/pubmed/27685888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163790
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