Three Dimensional Human Neuro-Spheroid Model of Alzheimer’s Disease Based on Differentiated Induced Pluripotent Stem Cells

The testing of candidate drugs to slow progression of Alzheimer’s disease (AD) requires clinical trials that are lengthy and expensive. Efforts to model the biochemical milieu of the AD brain may be greatly facilitated by combining two cutting edge technologies to generate three-dimensional (3D) hum...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Lee, Han-Kyu, Velazquez Sanchez, Clara, Chen, Mei, Morin, Peter J., Wells, John M., Hanlon, Eugene B., Xia, Weiming
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042502/
https://ncbi.nlm.nih.gov/pubmed/27684569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163072
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