The Efficacy of Natalizumab versus Fingolimod for Patients with Relapsing-Remitting Multiple Sclerosis: A Systematic Review, Indirect Evidence from Randomized Placebo-Controlled Trials and Meta-Analysis of Observational Head-to-Head Trials

BACKGROUND: Although Fingolimod (FGD) and Natalizumab (NTZ) appear to be effective in relapsing-remitting multiple sclerosis (RRMS), they have never been directly compared in a randomized clinical trial (RCT). METHODS AND FINDINGS: We evaluated the comparative efficacy of FGD vs. NTZ using a meta-an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tsivgoulis, Georgios, Katsanos, Aristeidis H., Mavridis, Dimitris, Grigoriadis, Nikolaos, Dardiotis, Efthymios, Heliopoulos, Ioannis, Papathanasopoulos, Panagiotis, Karapanayiotides, Theodoros, Kilidireas, Constantinos, Hadjigeorgiou, Georgios M., Voumvourakis, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042498/
https://ncbi.nlm.nih.gov/pubmed/27684943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163296
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