The CARD9 Polymorphisms rs4077515, rs10870077 and rs10781499 Are Uncoupled from Susceptibility to and Severity of Pulmonary Tuberculosis

Genetic variants in the CARD9 gene predispose to inflammatory disorders and chronic infectious diseases. Tuberculosis (TB), a chronic infectious disease affecting the lung, is lethal in Card9-deficient mice. We hypothesized that polymorphisms in the CARD9 gene influence TB progression and disease-as...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Streata, Ioana, Weiner, January, Iannaconne, Marco, McEwen, Gayle, Ciontea, Marius Sorin, Olaru, Marian, Capparelli, Rosanna, Ioana, Mihai, Kaufmann, Stefan H. E., Dorhoi, Anca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042433/
https://ncbi.nlm.nih.gov/pubmed/27684065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163662
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