Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments

BACKGROUND & AIMS: Crohn’s Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when activated intestinal fibroblasts deposit excessive amounts of extracellular matrix (ECM) in affected areas. A major component of the ECM is...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Soroosh, Artin, Albeiroti, Sami, West, Gail A., Willard, Belinda, Fiocchi, Claudio, de la Motte, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042354/
https://ncbi.nlm.nih.gov/pubmed/27981209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.12.007
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