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Outcome of Adult Brain Tumor Consortium (ABTC) prospective dose-finding trials of I-125 balloon brachytherapy in high-grade gliomas: challenges in clinical trial design and technology development when MRI treatment effect and recurrence appear similar

OBJECTIVES: The aim of this study is to define the maximal safe radiation dose to guide further study of the GliaSite balloon brachytherapy (GSBT) system in untreated newly diagnosed glioblastoma (NEW-GBM) and recurrent high-grade glioma (REC-HGG). GBST is a balloon placed in the resection cavity an...

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Detalhes bibliográficos
Publicado no:J Radiat Oncol
Main Authors: Kleinberg, L. R., Stieber, V., Mikkelsen, T., Judy, K., Weingart, J., Barnett, G., Olson, J., Desideri, S., Ye, X., Grossman, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042347/
https://ncbi.nlm.nih.gov/pubmed/27695605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13566-015-0210-y
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