Evaluation of optimum conditions for pachyman encapsulated in poly(d,l-lactic acid) nanospheres by response surface methodology and results of a related in vitro study

This study aimed to optimize the preparation conditions of pachyman (PHY)-loaded poly(d,l-lactic acid) (PLA) (PHYP) nanospheres by response surface methodology, explore their characteristics, and assess their effects on splenic lymphocytes. Double emulsion solvent evaporation was used to synthesize...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zheng, Sisi, Luo, Li, Bo, Ruonan, Liu, Zhenguang, Xing, Jie, Niu, Yale, Hu, Yuanliang, Liu, Jiaguo, Wang, Deyun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042191/
https://ncbi.nlm.nih.gov/pubmed/27729787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S115742
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