Molecular mechanisms of substrate specificities of uridinecytidine kinase

A uridine-cytidine kinase (UCK) catalyzes the phosphorylation of uridine (Urd) and cytidine (Cyd) and plays a significant role in the pyrimidine-nucleotide salvage pathway. Unlike ordinary ones, UCK from Thermus thermophilus HB8 (ttCK) loses catalytic activity on Urd due to lack of a substrate bindi...

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Detalhes bibliográficos
Publicado no:Biophys Physicobiol
Main Authors: Tanaka, Wataru, Shoji, Mitsuo, Tomoike, Fumiaki, Ujiie, Yuzuru, Hanaoka, Kyohei, Harada, Ryuhei, Kayanuma, Megumi, Kamiya, Katsumasa, Ishida, Toyokazu, Masui, Ryoji, Kuramitsu, Seiki, Shigeta, Yasuteru
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society of Japan (BSJ) 2016
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042166/
https://ncbi.nlm.nih.gov/pubmed/27924260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.13.0_77
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