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Targeting Glioma with a Dual Mode Optical and Paramagnetic Nanoprobe across the Blood-brain Tumor Barrier

In brain tumors, delivering nanoparticles across the blood-tumor barrier presents major hurdles. A clinically relevant MRI contrast agent, GdDOTA and a near-infrared (NIR) fluorescent dye, DL680 were conjugated to a G5 PAMAM dendrimer, thus producing a dual-mode MRI and NIR imaging agent. Systemic d...

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Detalhes bibliográficos
Publicado no:J Nanomed Nanotechnol
Main Authors: Karki, Kishor, Ewing, James R, Ali, Meser M
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042151/
https://ncbi.nlm.nih.gov/pubmed/27695645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7439.1000395
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