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Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease

OBJECTIVE: To investigate CSF biomarkers of neuroinflammation and neurodegeneration in Huntington disease (HD) gene-expansion carriers compared to controls and to investigate these biomarkers in association with clinical HD rating scales and disease burden score. METHODS: We collected CSF from 32 pr...

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Detalhes bibliográficos
Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Vinther-Jensen, Tua, Börnsen, Lars, Budtz-Jørgensen, Esben, Ammitzbøll, Cecilie, Larsen, Ida U., Hjermind, Lena E., Sellebjerg, Finn, Nielsen, Jørgen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042104/
https://ncbi.nlm.nih.gov/pubmed/27734023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000287
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