Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma

The non-classical human leukocyte antigen G (HLA-G) is expressed at a high frequency in renal cell carcinoma (RCC) and is associated with a higher tumor grade and a poor clinical outcome. This might be caused by the HLA-G-mediated inhibition of the cytotoxicity of T and NK cells. Therefore a selecti...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Jasinski-Bergner, Simon, Reches, Adi, Stoehr, Christine, Massa, Chiara, Gonschorek, Evamaria, Huettelmaier, Stefan, Braun, Juliane, Wach, Sven, Wullich, Bernd, Spath, Verena, Wang, Ena, Marincola, Francesco M., Mandelboim, Ofer, Hartmann, Arndt, Seliger, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042021/
https://ncbi.nlm.nih.gov/pubmed/27057628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8567
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