Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma

In human tumors of distinct origin including renal cell carcinoma (RCC), the non-classical human leukocyte antigen G (HLA-G) is frequently expressed, thereby inhibiting the cytotoxic activity of T and natural killer (NK) cells. Recent studies demonstrated a strong post-transcriptional gene regulatio...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Jasinski-Bergner, Simon, Stoehr, Christine, Bukur, Juergen, Massa, Chiara, Braun, Juliane, Hüttelmaier, Stefan, Spath, Verena, Wartenberg, Roland, Legal, Wolfgang, Taubert, Helge, Wach, Sven, Wullich, Bernd, Hartmann, Arndt, Seliger, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485830/
https://ncbi.nlm.nih.gov/pubmed/26155421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1008805
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