Establishment of prostate cancer spheres from a prostate cancer cell line after phenethyl isothiocyanate treatment and discovery of androgen-dependent reversible differentiation between sphere and neuroendocrine cells

Prostate cancer can transform from androgen-responsive to an androgen-independent phenotype. The mechanism responsible for the transformation remains unclear. We studied the effects of an epigenetic modulator, phenethyl isothiocyanate (PEITC), on the androgen-responsive LNCaP cells. After treatment...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Yamei, Cang, Shundong, Han, Liying, Liu, Christina, Yang, Patrick, Solangi, Zeeshan, Lu, Quanyi, Liu, Delong, Chiao, J.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041999/
https://ncbi.nlm.nih.gov/pubmed/27034170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8440
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