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Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients

Germline and somatic mutations play a crucial role in breast cancer (BC), driving the initiation, progression, response to therapy and outcome of the disease. Hormonal therapy is limited to patients with tumors expressing steroid hormone receptors, such as estrogen receptor (ER), nevertheless resist...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Griseri, Paola, Garrone, Ornella, Lo Sardo, Alessandra, Monteverde, Martino, Rusmini, Marta, Tonissi, Federica, Merlano, Marco, Bruzzi, Paolo, Lo Nigro, Cristiana, Ceccherini, Isabella
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041993/
https://ncbi.nlm.nih.gov/pubmed/27034161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8417
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