REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Prostate cancer (PCa) with neuroendocrine differentiation (NED) is tightly associated with hormone refractory PCa (HRPC), an aggressive form of cancer that is nearly impossible to treat. Determining the mechanism of the development of NED may yield novel therapeutic strategies for HRPC. Here, we fir...

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Publicat a:Oncotarget
Autors principals: Lin, Tzu-Ping, Chang, Yi-Ting, Lee, Sung-Yuan, Campbell, Mel, Wang, Tien-Chiao, Shen, Shu-Huei, Chung, Hsiao-Jen, Chang, Yen-Hwa, Chiu, Allen W., Pan, Chin-Chen, Lin, Chi-Hung, Chu, Cheng-Ying, Kung, Hsing-Jien, Cheng, Chia-Yang, Chang, Pei-Ching
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041970/
https://ncbi.nlm.nih.gov/pubmed/27034167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8433
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