HDAC1 controls CIP2A transcription in human colorectal cancer cells

This work describes the effectiveness of HDAC-inhibitor (S)-2 towards colorectal cancer (CRC) HCT116 cells in vitro by inducing cell cycle arrest and apoptosis, and in vivo by contrasting tumour growth in mice xenografts. Among the multifaceted drug-induced events described herein, an interesting li...

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Опубликовано в: :Oncotarget
Главные авторы: Balliu, Manjola, Cellai, Cristina, Lulli, Matteo, Laurenzana, Anna, Torre, Eugenio, Vannucchi, Alessandro Maria, Paoletti, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041950/
https://ncbi.nlm.nih.gov/pubmed/27029072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8406
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