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The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells

Increasing evidence supports that the epithelial to mesenchymal transition (EMT) in breast cancer cells generates tumor initiating cells (TICs) but the contribution of the tumor microenvironment to these programs needs further elucidation. CCN6 (WISP3) is a secreted matrix-associated protein (36.9 k...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Wei, Martin, Emily E., Burman, Boris, Gonzalez, Maria E., Kleer, Celina G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041896/
https://ncbi.nlm.nih.gov/pubmed/26933820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7734
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