Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression

Tumor cells are confronted to a type I collagen rich environment which regulates cell proliferation and invasion. Biological aging has been associated with structural changes of type I collagen. Here, we address the effect of collagen aging on cell proliferation in a three-dimensional context (3D)....

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Bibliographic Details
Published in:Oncotarget
Main Authors: Saby, Charles, Buache, Emilie, Brassart-Pasco, Sylvie, El Btaouri, Hassan, Courageot, Marie-Pierre, Van Gulick, Laurence, Garnotel, Roselyne, Jeannesson, Pierre, Morjani, Hamid
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper: Gerotarget (Focus on Aging)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041879/
https://ncbi.nlm.nih.gov/pubmed/27121132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8795
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