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Preparation and preclinical evaluation of (68)Ga-DOTA-amlodipine for L-type calcium channel imaging
AIM: In order to develop a possible tracer for L-type calcium channel imaging, we here report the development of a Ga-68 amlodipine derivative for possible PET imaging. MATERIALS AND METHODS: Amlodipine DOTA conjugate was synthesized, characterized and went through calcium channel blockade, toxicity...
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| Publié dans: | Indian J Nucl Med |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Medknow Publications & Media Pvt Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041414/ https://ncbi.nlm.nih.gov/pubmed/27833311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0972-3919.190797 |
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