Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

We recently reported the discovery of a series of bioactive prostaglandin F2-like compounds (F2-isoprostanes) that are produced in vivo by free radical-catalyzed peroxidation of arachidonic acid independent of the cyclooxygenase enzyme. Inasmuch as phospholipids readily undergo peroxidation, we exam...

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Dades bibliogràfiques
Autors principals: Morrow, J D, Awad, J A, Boss, H J, Blair, I A, Roberts, L J
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC50413/
https://ncbi.nlm.nih.gov/pubmed/1438268
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