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Functional Annotations of Paralogs: A Blessing and a Curse
Gene duplication followed by mutation is a classic mechanism of neofunctionalization, producing gene families with functional diversity. In some cases, a single point mutation is sufficient to change the substrate specificity and/or the chemistry performed by an enzyme, making it difficult to accura...
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| Publicado no: | Life (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041015/ https://ncbi.nlm.nih.gov/pubmed/27618105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life6030039 |
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