Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities

Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the NOX subunits with an uncontrolled manner. Therefore, targeting neutrophil...

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Detalhes bibliográficos
Publicado no:Lipids
Main Authors: Liu, Miao, Boussetta, Tarek, Makni-Maalej, Karama, Fay, Michèle, Driss, Fathi, El-Benna, Jamel, Lagarde, Michel, Guichardant, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Oil Chemists' Society 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040756/
https://ncbi.nlm.nih.gov/pubmed/24254970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-013-3863-6
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