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Natural Mosquito-Pathogen Hybrid IgG4 Antibodies in Vector-Borne Diseases: A Hypothesis

Chronic exposure to antigens may favor the production of IgG4 antibodies over other antibody types. Recent studies have shown that up to a 30% of normal human IgG4 is bi-specific and is able to recognize two antigens of different nature. A requirement for this specificity is the presence of both eli...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Londono-Renteria, Berlin, Cardenas, Jenny C., Troupin, Andrea, Colpitts, Tonya M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040711/
https://ncbi.nlm.nih.gov/pubmed/27746778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00380
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