Using baseline cognitive severity for enriching Alzheimer's disease clinical trials: How does Mini-Mental State Examination predict rate of change?

BACKGROUND: Post hoc analyses from clinical trials in Alzheimer's disease (AD) suggest that more cognitively impaired participants respond differently from less impaired on cognitive outcomes. We examined pooled clinical trials data to assess the utility of enriching trials using baseline cogni...

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Publicado en:Alzheimers Dement (N Y)
Autores principales: Kennedy, Richard E., Cutter, Gary R., Wang, Guoqiao, Schneider, Lon S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040516/
https://ncbi.nlm.nih.gov/pubmed/27695707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2015.03.001
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