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Sodium-glucose cotransporter 2 inhibition and health benefits: The Robin Hood effect

This review discusses two distinct, yet related, mechanisms of sodium-glucose cotransporter 2 (SGLT2) inhibition: Calorie restriction mimicry (CRM) and pro-ketogenic effect, which may explain their cardiovascular benefits. We term these adaptive CRM and pro-ketogenic effects of SGLT2 inhibition, the...

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Veröffentlicht in:Indian J Endocrinol Metab
Hauptverfasser: Kalra, Sanjay, Jain, Arpit, Ved, Jignesh, Unnikrishnan, A. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040058/
https://ncbi.nlm.nih.gov/pubmed/27730088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-8210.183826
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