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Shared HLA class II-associated genetic susceptibility and resistance, related to the HLA-DQB1 gene, in IgA deficiency and common variable immunodeficiency.

Most cases of selective IgA deficiency (IgA-D) and common variable immunodeficiency (CVID) occur sporadically. However, familial clustering is not uncommon, and the two disorders can occur within the same family. We have previously described positive associations with three DR-DQ haplotypes as well...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Olerup, O, Smith, C I, Björkander, J, Hammarström, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10653
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