Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment

In this study, to model 3D chemotactic tumor-stroma invasion in vitro, we developed an innovative microfluidic chip allowing side-by-side positioning of 3D hydrogel-based matrices. We were able to (1) create a dual matrix architecture that extended in a continuous manner, thus allowing invasion from...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Truong, Danh, Puleo, Julieann, Llave, Alison, Mouneimne, Ghassan, Kamm, Roger D., Nikkhah, Mehdi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039718/
https://ncbi.nlm.nih.gov/pubmed/27678304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34094
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